Lipids and Lipid Derivatives
Medchemexpress LLC Oleic acid alkyne | 151333-45-8 | 99.8% | 1 MG
Oleic acid alkyne is oleic acid with an acetylene group. The terminal alkyne group facilitates click chemical ligation reactions, enabling the introduction of fluorescent or biotin-labeled oleic acid. It can also be hydroxylated by a microsomal cytochrome P-450-dependent system (ω-OAH), allowing for analysis of its metabolism and biological activity.
- Features a terminal alkyne group for click chemistry
- Supports fluorescent or biotin labeling of oleic acid
- Applicable for analyzing metabolism and biological activity
- Can be hydroxylated by a microsomal cytochrome P-450-dependent system (ω-OAH)
Medchemexpress LLC Vitamin D3 | 67-97-0 | C27H44O | 5 G
Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occurring form of vitamin D. It induces cell differentiation and prevents the proliferation of cancer cells, playing a crucial role in various biological activities for research use.
- Naturally occurring form of vitamin D.
- Induces cell differentiation and prevents proliferation of cancer cells.
- Undergoes two hydroxylation processes to become biologically active in vivo.
- Active form is 1,25-dihydroxycholecalciferol (calcitriol).
- Exhibits anti-proliferative effects in various cell lines in a dose- and time-dependent manner.
- Increases nuclear VDR staining and produces local VDR activation in IK cells.
- Potentiates CCl4 toxicity in the liver and increases renal calcium levels in mice in vivo.
Medchemexpress LLC 5,6-trans-vitamin D2 | 51744-66-2 | 97.0% | C28H44O | 50 MG
5,6-trans-Vitamin D2 is an isomer of Vitamin D2. It is for research use only. This product is an off-white to light yellow solid.
- Isomer of Vitamin D2
- Off-white to light yellow solid
- For research use only
- Solubility in DMSO: 25 mg/mL (63.03 mM)
- Recommended storage for solid: -20°C, protect from light, stored under nitrogen
- Recommended storage in solvent: -80°C for 6 months, or -20°C for 1 month (protect from light, stored under nitrogen)
Medchemexpress LLC Alosetron-d3 hydrochloride | 1189919-71-8 | 99.0% | C17H16D3ClN4O | 5 MG
Alosetron-d3 hydrochloride is a deuterium labeled Alosetron, functioning as a serotonin 5HT3-receptor antagonist. It is suitable for use as a tracer and an internal standard in NMR, GC-MS, or LC-MS analysis for quantitative applications.
- Deuterium labeled compound
- Serotonin 5HT3-receptor antagonist
- Internal standard for quantitative analysis
- Used in neurological disease research
- Supports drug concentration detection
Medchemexpress LLC 1-Methylinosine-d3 | 2140-73-0 | 99.0% | 285.27 | 1 MG
1-Methylinosine-d3 is a deuterium-labeled version of 1-Methylinosine. 1-Methylinosine is a modified nucleotide found at position 37 in the tRNA 3' to the anticodon of eukaryotic tRNA. This product is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can affect pharmacokinetic and metabolic profiles.
Medchemexpress LLC 1α,25-dihydroxy-3-epi-vitamin D3 | 61476-45-7 | MFCD28963706 | 98.5% | 416.64 g·mol⁻1 | C27H44O3 | 5 MG
1S-Calcitriol is a stereoisomer of calcitriol (1α,25-dihydroxyvitamin D3) that functions as a potent vitamin D receptor (VDR) agonist. It is provided as a high-purity solid research reagent for use in cellular, biochemical, and pharmacological studies of VDR signaling, calcium homeostasis, and related physiological processes.
- Potent vitamin D receptor agonist.
- Useful for studying keratinocyte proliferation and differentiation.
- Supports investigation of parathyroid hormone regulation and calcium signaling.
- Provided as a high-purity solid for analytical and biological assays.
- Chemical formula C27H44O3; molecular weight 416.64 g·mol⁻1.
Cambridge Isotope Laboratories Melatonin (acetyl-D3 98%) CP 95% 10 mg
Melatonin (acetyl-D3 98%) CP 95% 10 mg
Medchemexpress LLC Trans-doxercalciferol | 74007-20-8 | MFCD01076571 | 98.2% | 412.65 | C28H44O2 | 10 MG
trans-Doxercalciferol is an isomer of doxercalciferol (a vitamin D2 analog) that activates the vitamin D receptor (VDR). Supplied as a research-grade powder for in vitro and analytical use, it has a molecular weight of 412.65 g/mol and a reported purity of 98.2%.
- Is an isomer of doxercalciferol and a vitamin D2 analog.
- Activates the vitamin D receptor (VDR) and is used in vitamin D signaling research.
- High reported purity (98.2%).
- Available in multiple pack sizes, including 10 mg.
- Powder storage: -20°C for long-term, 4°C for short-term stability.
Medchemexpress LLC Vitamin D2 (Ergocalciferol) | 50-14-6 | 99.1% | C28H44O | 1 G
Vitamin D2, also known as Ergocalciferol, Calciferol, or Ercalciol, is derived from plant sources or dietary supplements and functions as a Vitamin D supplement. This compound is classified under steroids and is an endogenous metabolite found in plants and human gut microbiota.
- Derived from plant sources or dietary supplements
- Functions as a vitamin D supplement
- Classified as a steroid
- Endogenous metabolite found in plants and human gut microbiota
- Appears as a white to light yellow solid
- For research use only
Medchemexpress LLC Cinnamoylglycine-2,2-d2 | 1219806-46-8 | 99.4% | C11H9D2NO3 | 1 MG
Cinnamoylglycine-2,2-d2 is a white to off-white solid with a purity of 99.40% (HPLC). It is suitable for research use only and has not been fully validated for medical applications.
- Consistent with structure (1 H NMR Spectrum)
- Product has been tested and complies with specifications
eMolecules 58050-55-8 | Medchem Express | 24 25-Dihydroxy VD2 | 1mg | 446271510 | HY-76801 | 428.657 | C28H44O3
Medchem Express | 24 25-Dihydroxy VD2 | 1mg | 446271510 | HY-76801 | 58050-55-8 | 428.657 | C28H44O3
Cayman Chemical Resolvin D2 Neurochemicals
A product of the action of 15- and 5-LO on DHA; dampens excessive neutrophil trafficking to sites of inflammation; reduces zymosan-stimulated PMN infiltration by 70% at 10 pg per mouse; reduces PAF-stimulated leukocyte adherence and emigration at 1 nM; stimulates nitric oxide production decreases leukocyte-endothelial interactions; reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance in a mouse model of sepsis
Cayman Chemical LnolIn VItamIn D3 5g
A biologically inactive precursor to calcitriol converted to active metabolites in vivo; obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol to previtamin D3 by UVB radiation, followed by isomerization to vitamin D3; can be converted to 25-hydroxy vitamin D3 in the liver by CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney
Medchemexpress LLC Thymidine-α,α,α-d3 | 74848-84-3 | 245.25 | 1 MG
Thymidine-d3 is deuterium labeled Thymidine, a specific precursor of deoxyribonucleic acid used as a cell synchronizing agent. It functions as a DNA synthesis inhibitor, capable of arresting cells at the G1/S boundary before DNA replication. Deuterium substitution has the potential to affect pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Cyclin D3/CCND3 Antibody (YA484) | Predicted band size: 33 kDa; Observed band size: 33 kDa | 50 UL
Cyclin D3/CCND3 Antibody (YA484) | Predicted band size: 33 kDa; Observed band size: 33 kDa | 50 UL